{"id":5346,"date":"2024-01-16T09:56:11","date_gmt":"2024-01-16T08:56:11","guid":{"rendered":"https:\/\/zoe4life.org\/?post_type=projets-de-recherche&#038;p=5346"},"modified":"2024-01-16T10:01:18","modified_gmt":"2024-01-16T09:01:18","slug":"hereditary-predisposition-to-childhood-cancer","status":"publish","type":"projets-de-recherche","link":"https:\/\/zoe4life.org\/en\/research-projects\/hereditary-predisposition-to-childhood-cancer\/","title":{"rendered":"Hereditary predisposition to childhood cancers"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"5346\" class=\"elementor elementor-5346\" data-elementor-post-type=\"projets-de-recherche\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cd2513d e-con-full e-flex e-con e-parent\" data-id=\"cd2513d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;shape_divider_bottom&quot;:&quot;curve&quot;,&quot;shape_divider_bottom_negative&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" aria-hidden=\"true\" data-negative=\"true\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 1000 100\" preserveaspectratio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M500,97C126.7,96.3,0.8,19.8,0,0v100l1000,0V1C1000,19.4,873.3,97.8,500,97z\"\/>\n<\/svg>\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3b37b86 e-con-full e-flex e-con e-child\" data-id=\"3b37b86\" data-element_type=\"container\" data-settings=\"{&quot;shape_divider_bottom&quot;:&quot;curve&quot;,&quot;shape_divider_bottom_negative&quot;:&quot;yes&quot;,&quot;position&quot;:&quot;absolute&quot;}\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" aria-hidden=\"true\" data-negative=\"true\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 1000 100\" preserveaspectratio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M500,97C126.7,96.3,0.8,19.8,0,0v100l1000,0V1C1000,19.4,873.3,97.8,500,97z\"\/>\n<\/svg>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c81153f e-flex e-con-boxed e-con e-parent\" data-id=\"c81153f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-001fe7e elementor-widget elementor-widget-heading\" data-id=\"001fe7e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><span>Hereditary predisposition <\/span> to childhood cancers<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8d6d5d8 e-flex e-con-boxed e-con e-parent\" data-id=\"8d6d5d8\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4707128 elementor-widget elementor-widget-heading\" data-id=\"4707128\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Study on hereditary predispositions to childhood cancers - screening and management.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3af7dde elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"3af7dde\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Pediatric cancer is a difficult ordeal for young patients and their families alike. Even if today's therapeutic options enable most children to be cured, cancer still imposes heavy, long-term treatments.<\/p><p>Unfortunately, children who have suffered from cancer tend to develop cancer again during their lives.<\/p><p><strong>A second cancer is the most frequent cause of death after recovery from a first childhood cancer.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e887a64 elementor-widget elementor-widget-heading\" data-id=\"e887a64\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Hereditary predisposition to cancerous diseases may explain a significant proportion of second cancers.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-830d879 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"830d879\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As a result, children and adults with a predisposition to childhood cancer require particularly close monitoring. This will enable us to detect a second cancer as early as possible, and to treat it at an early stage in a way that minimizes after-effects.<\/p><p>Clinical signs or a family history can reveal a predisposition to cancerous diseases.<\/p><p><strong>That's why people with certain characteristics can benefit from genetic counseling.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cfdd8ac e-flex e-con-boxed e-con e-parent\" data-id=\"cfdd8ac\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0248e32 e-flex e-con-boxed e-con e-child\" data-id=\"0248e32\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a2932e7 elementor-widget elementor-widget-image\" data-id=\"a2932e7\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"375\" src=\"https:\/\/zoe4life.org\/wp-content\/uploads\/2024\/01\/Dr-Waespe.jpeg\" class=\"attachment-large size-large wp-image-5349\" alt=\"\" srcset=\"https:\/\/zoe4life.org\/wp-content\/uploads\/2024\/01\/Dr-Waespe.jpeg 600w, https:\/\/zoe4life.org\/wp-content\/uploads\/2024\/01\/Dr-Waespe-300x188.jpeg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9f8b009 elementor-widget elementor-widget-heading\" data-id=\"9f8b009\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dr Nicolas Waespe<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6773f5a elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"6773f5a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Pediatric oncologist \/ hematologist in\u00a0<a href=\"http:\/\/www.kinderklinik.insel.ch\/de\/unser-angebot\/details\/person\/detail\/nicolas-waespe\" target=\"_blank\" rel=\"noopener\">Berne Island University Hospital<\/a>is responsible for this study.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-685ba31 e-flex e-con-boxed e-con e-child\" data-id=\"685ba31\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5ce4c76 elementor-widget elementor-widget-heading\" data-id=\"5ce4c76\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">How the study works<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-234ee26 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"234ee26\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Between January 2022 and December 2023, doctors and patients will be surveyed to determine which patients are being screened.<\/p><p>A questionnaire will be sent to pediatric oncologists in several European countries. The questionnaire concerns their approach to cancer screening and follow-up.<\/p><p>Survivors of childhood cancer will also receive a questionnaire. The questionnaire asks about signs of hereditary predisposition and screening.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-13f2746 e-flex e-con-boxed e-con e-parent\" data-id=\"13f2746\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-317c81a elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"317c81a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The aim of the study is to find out whether and how patients were offered genetic counseling in the presence of signs of cancer predisposition. The study will show where there is potential for improvement. Finally, it aims to contribute to improving management and survival after childhood cancer.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2b8d39d elementor-widget elementor-widget-heading\" data-id=\"2b8d39d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Zo\u00e94life financed this study to the tune of CHF 61,720 in 2022.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5f719c3 e-con-full e-flex e-con e-parent\" data-id=\"5f719c3\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-f6d49df e-flex e-con-boxed e-con e-child\" data-id=\"f6d49df\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_range&quot;:&quot;viewport&quot;,&quot;background_motion_fx_translateY_direction&quot;:&quot;negative&quot;,&quot;background_motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:4,&quot;sizes&quot;:[]},&quot;background_motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;laptop&quot;,&quot;tablet_extra&quot;,&quot;tablet&quot;,&quot;mobile_extra&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8efe5df e-flex e-con-boxed e-con e-child\" data-id=\"8efe5df\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-08d15d3 elementor-widget-mobile__width-initial elementor-widget__width-initial elementor-widget-mobile_extra__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"08d15d3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Our other actions :<\/p><p><a class=\"button white is-link expand\" href=\"https:\/\/zoe4life.org\/en\/research-and-new-treatments\/\">RESEARCH AND NEW TREATMENTS<\/a><\/p><p><a class=\"button white is-link expand\" href=\"https:\/\/zoe4life.org\/en\/family-support\/\">FAMILY SUPPORT<\/a><\/p><p><a class=\"button white is-link expand no-margin no-padding\" href=\"https:\/\/zoe4life.org\/en\/projects-for-children\/\">PROJECTS FOR CHILDREN<\/a><\/p><p><a class=\"button white is-link expand no-margin no-padding\" href=\"https:\/\/zoe4life.org\/en\/sensibiliser-cancer-enfant\/\" target=\"_self\">PUBLIC AWARENESS\u00a0<i class=\"icon-angle-right\"><\/i><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cf2bf9e e-flex e-con-boxed e-con e-parent\" data-id=\"cf2bf9e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d99401b e-flex e-con-boxed e-con e-child\" data-id=\"d99401b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-43cbaaf elementor-widget elementor-widget-image\" data-id=\"43cbaaf\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"629\" height=\"848\" src=\"https:\/\/zoe4life.org\/wp-content\/uploads\/2023\/10\/poupee-baskets.png\" class=\"attachment-large size-large wp-image-751\" alt=\"\" srcset=\"https:\/\/zoe4life.org\/wp-content\/uploads\/2023\/10\/poupee-baskets.png 629w, https:\/\/zoe4life.org\/wp-content\/uploads\/2023\/10\/poupee-baskets-223x300.png 223w\" sizes=\"(max-width: 629px) 100vw, 629px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-57d362b e-flex e-con-boxed e-con e-child\" data-id=\"57d362b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0575c28 elementor-widget elementor-widget-heading\" data-id=\"0575c28\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><span>Together<\/span> we can make a difference<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a2ebdf elementor-widget elementor-widget-text-editor\" data-id=\"7a2ebdf\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>There are many ways to support us. Your commitment makes a difference for children with cancer.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5bd954e elementor-align-left elementor-widget elementor-widget-global elementor-global-4109 elementor-widget-button\" data-id=\"5bd954e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pay.raisenow.io\/btpnw?lng=fr\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"Calque_1\" x=\"0px\" y=\"0px\" viewbox=\"0 0 50 50\" style=\"enable-background:new 0 0 50 50;\" xml:space=\"preserve\">    <style 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